My current research aims to engineer yeast for production of biofuels. During my PhD I worked on enzyme mechanisms and catalytic promiscuity.
PhD (2010) Biochemistry, Cambridge University, UK
MSci & BA (2006) Natural Sciences, Cambridge University, UK
Babtie A, Tokuriki N, Hollfelder F (2010) What makes an enzyme promiscuous? Curr Opin Chem Biol (14) 200-7
van Loo B, Jonas S, Babtie A, Benjdia A, Berteau O, Hyvonen M, Hollfelder F (2010) An efficient, multiply promiscuous hydrolase in the alkaline phosphatase superfamily. Proc Natl Acad Sci (107) 2740-5
Babtie A, Bandyopadhyay S, Olguin LF, Hollfelder F (2009) Efficient catalytic promiscuity for chemically distinct reactions. Angew Chem Int Ed (48) 3692-4
Shim J, Olguin L, Whyte G, Scott D, Babtie A, Abell C, Huck W, Hollfelder F (2009) Simultaneous determination of gene expression and enzymatic activity in individual bacterial cells in microdroplet compartments. J Am Chem Soc (131) 15251–6