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Orhan Karsligil

Education

MASSACHUSETTS INSTITUTE OF TECHNOLOGY Cambridge, MA
Laboratory of Intelligent Systems in Process Engineering
Ph.D. degree in Chemical Engineering, June 2000.

Thesis under Prof. George Stephanopoulos on “Multiscale Modeling, Identification, and Model Predictive Control of Procoptimization algorithms in Quadratic Programming achieving orders of magnitude reduction in complexityessing Systems.” Minor in Nonlinear Mathematics. Applied wavelets to modeling and optimization in order to capture multirate and multiscale features. Created new .

Elected member of Sigma Xi and past member of AICHE. Twice elected as president of M.I.T. Turkish Students Association.

BOGAZICI UNIVERSITY Istanbul, TURKEY
B.S. in Chemical Engineering, June 1995.

Graduated with High Honors in seven semesters. Emphasis on process design and economics, control, and optimization. Final project on “Developing a Controllability Index for Heat Exchanger Networks with Bypass Streams.

Experience

08/09-Present
THEISS RESEARCH (http://theissresearch.org/)

Scientist / Principal Investigator on research projects involving process design and control, signal processing and pattern recognition.

11/05-Present
MASSACHUSETTS INSTITUTE OF TECHNOLOGY Cambridge, MA
Bioinformatics and Metabolic Engineering Laboratory

Research Scholar working on network and pattern identification problems, specifically on computational design of Antimicrobial Peptides using motifs extracted from known peptides.

09/00-Present
THE EXETER GROUP, INC. Cambridge, MA
Head of Information Systems, Project Manager

Client-facing experience includes leading the development of Online Enrollment Application of a large US University as a Project Manager, managing the upgrade of student management systems for a university in Kuwait as an Assistant Project Manager, designing the security architecture for a B2B project between a prominent bank and an airline company in Kuwait as an Operations Lead, and implementation of Exeter Student Suite for a leading medical school in Boston.

Internal project experience includes managing the IT team, managing the upgrade and expansion of the internal IS infrastructure, planning and implementing security policies and audits for the Exeter network, developing strategies and completing the implementation of an Exeter-wide content management system, and developing and implementing Exeter Group’s intranet systems including expense and time tracking, invoicing, reporting, and allocations.

MCSE and MCDBA certifications.

8/95-6/00
MASSACHUSETTS INSTITUTE OF TECHNOLOGY Cambridge, MA
Laboratory for Intelligent Systems in Process Engineering

Research Assistant, Teaching Assistant, Seminar Series Organizer, and Systems Administrator.

Summer 1994
PROCTER & GAMBLE, INC. Frankfurt, GERMANY
First Line Manager, European Beverages Process Development Department.

Project on the solubility of calcium complexes in orange juice concentrate

Publications

  • “Multi-Scale Modeling, Estimation and Control of Processing Systems”, George Stephanopoulos, Matthew Dyer, and Orhan Karsligil, Computers and Chemical Engineering, 21, p. S797-S803 (1997)
  • “Multi-Scale Considerations in Linear and Nonlinear Estimation and Control”, George Stephanopoulos, Orhan Karsligil and Matthew Dyer, in Nonlinear Model-Based Control, R. Berber and C. Kravaris (editors), Kluwer (1998)
  • “Multi-Scale Model-Predictive Control”, Orhan Karsligil, Matthew Dyer and George Stephanopoulos, Proceedings of DYCOPS-5, Kerkyra, Greece (1998)
  • “Multi-scale Aspects in Model-Predictive Control”, George Stephanopoulos, Orhan Karsligil, and Matthew Dyer, Journal of Process Control, Vol: 10, Issue: 2-3, pp. 275-282 (2000)
  • “Multiscale theory for linear dynamic processes: Part 1. Foundations”, George Stephanopoulos, Orhan Karsligil, Matthew S. Dyer, Computers & Chemical Engineering, Volume 32, Issues 4-5, 5 April 2008, Pages 857-884
  • “Multiscale theory for linear dynamic processes: Part 2. Multiscale model predictive control (MS-MPC)”, George Stephanopoulos, Orhan Karsligil, Matthew S. Dyer, Computers & Chemical Engineering, Volume 32, Issues 4-5, 5 April 2008, Pages 885-912

Research Interests
Rational Design of Peptides with Desired Properties

Using techniques from motif discovery and machine learning extract grammars from a database of peptides sharing a unique property. Using these grammars and other design techniques create candidate peptides with desired characteristics.

Timeseries Analysis

Using ideas from multiscale analysis, machine learning, trend analysis and pattern discovery devise new algorithms to deconstruct timeseries into various components and to predict future values.

Satellite Image Analysis

Devise algorithms adapted from financial timeseries analysis techniques to detect deception.

Awards

  • PAD scholarship from German Government 1984
  • 3rd place in Turkish Physics Olympiads, 1986
  • Valedictorian, Istanbul German High School, 1991
  • DAAD scholarship from the German Government, 1991
  • Bogazici Univ. Alumni Association Scholarship, 1991-1995
  • Bogazici Univ. Professor Turgut Noyan Award, 1995
  • M.I.T. Chem. Eng. Dept. Graduate Student Fellowship, 1995

Activities

  • Turkish-American Cultural Society of New England, Inc.
  • Twice elected as Member of the Executive Committee, serving on the Disciplinary Committee

Languages

Fluent in English, German, and Turkish.