Search results for 'Hal'

The world is entering a transition period, one in which we are progressing from a fossil-based economy to a bio-based economy.  In a bio-based economy, items such as fuels, chemicals, and materials will be derived from biological sources, which offer several advantages over fossil-based sources; however, technological advances are required.  Our lab is currently conducting research in this field, on [...]

The isoprenoid “superfamily” has generated considerable interest among the scientific community in recent years owing to the demonstrated therapeutic potential of several of its 40,000-odd members. Prominent among these are menthol, artemisinin, lycopene and taxol. The high specificity and efficacy of these molecules have caught the attention of several large pharmaceutical corporations, and many in [...]

Research Interests During tumorigenesis, cells undergo metabolic transformation to support proliferation, being aerobic glycolysis a hallmark of cancer. My research employs stable isotopes to determine further metabolic shifts associated with aberrant growth. Education B.S. (2008) Biochemistry; University of Coimbra, Portugal E-mail: pgameiro@mit.edu

Engineering tolerance in yeast for improved ethanol production Baker’s yeast Saccharomyces cerevisiae is the organism of choice for the conversion of plant sugar (from corn or sugarcane, currently) to ethanol biofuel. At present, cellular toxicity to substrates or products in the fermentation medium remains one of the primary limitations of higher ethanol production. For example, [...]

Books Gregory N. Stephanopoulos, Aristos A. Aristidou, Jens Nielsen. Metabolic engineering. San Diego: Academic Press, 1998. isbn:0126662606. [1B] edited by Isidore Rigoutsos and Gregory Stephanopoulos. Systems biology. New York: Oxford University Press, 2007. isbn:0195300815. [2B] edited by Isidore Rigoutsos and Gregory Stephanopoulos. Systems biology. New York: Oxford University Press, 2007. isbn:0195300807. [3B] Publications accessible in PubMed Tyo KE, Nevoigt E, Stephanopoulos G. Directed [...]